Article
Identification of CSF3R Mutations in B-Lineage Acute Lymphoblastic Leukemia Using Comprehensive Cancer Panel and Next-Generation Sequencing.
Genes - 27 Aug 2021
Rashid Mamoon, Alasiri Abdulrahman, Al Balwi Mohammad A, Alkhaldi Aziza, Alsuhaibani Ahmed, Alsultan Abdulrahman, Alharbi Talal, Alomair Lamya, Almuzzaini Bader
Abstract excerpt
B-lineage acute lymphocytic leukemia (B-ALL) is characterized by different genetic aberrations at a chromosomal and gene level which are very crucial for diagnosis, prognosis and risk assessment of the disease. However, there is still controversial arguments in regard to disease outcomes in specific genetic abnormalities, e.g., 9p-deletion. Moreover, in absence of cytogenetic abnormalities it is difficult to...
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