Article
Wave2 activates serum response element via its VCA region and functions downstream of Rac.
Experimental cell research - 10 Dec 2004
Ishiguro Kazuhiro, Cao Zhifang, Ilasca Marco Lopez, Ando Takafumi, Xavier Ramnik
Abstract excerpt
WAVE2 is a member of the WASP/WAVE family of protein effectors of actin reorganization and cell movement. In this report, we demonstrate that WAVE2 overexpression induces serum response element (SRE) activation through serum response factor. A WAVE2 mutant lacking the VCA region did not induce SR...
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