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Article

Loss of Dihydroxyacid Dehydratase Induces Auxotrophy in Bacillus anthracis.

Journal of bacteriology - 19 Nov 2021

Jelinski Joseph, Cortez Madeline, Terwilliger Austen, Clark Justin, Maresso Anthony

Abstract excerpt

Anthrax disease is caused by infection with the bacteria Bacillus anthracis which, if left untreated, can result in fatal bacteremia and toxemia. Current treatment for infection requires prolonged administration of antibiotics. Despite this, inhalational and gastrointestinal anthrax still result in lethal disease. By identifying key metabolic steps that B. anthracis uses to grow in host-like environments, new...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34570623
DOI: 10.1128/JB.00415-21
PMCID: PMC8604071

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