Article
Petrobactin Is Exported from Bacillus anthracis by the RND-Type Exporter ApeX.
mBio - 12 Sept 2017
Hagan A K, Tripathi A, Berger D, Sherman D H, Hanna P C
Abstract excerpt
Bacillus anthracis-a Gram-positive, spore-forming bacterium-causes anthrax, a highly lethal disease with high bacteremia titers. Such rapid growth requires ample access to nutrients, including iron. However, access to this critical metal is heavily restricted in mammals, which requires B. anthracis to employ petrobactin, an iron-scavenging small molecule known as a siderophore. Petrobactin biosynthesis is...
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