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Article

Epistasis for head morphology in Drosophila melanogaster.

G3 (Bethesda, Md.) - 27 Sept 2021

Özsoy Ergi D, Yılmaz Murat, Patlar Bahar, Emecen Güzin, Durmaz Esra, Magwire Michael M, Zhou Shanshan, Huang Wen, Anholt Robert R H, Mackay Trudy F C

Abstract excerpt

Epistasis-gene-gene interaction-is common for mutations with large phenotypic effects in humans and model organisms. Epistasis impacts quantitative genetic models of speciation, response to natural and artificial selection, genetic mapping, and personalized medicine. However, the existence and magnitude of epistasis between alleles with small quantitative phenotypic effects are controversial and difficult to...

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Identifiers

PMID: 34568933
DOI: 10.1093/g3journal/jkab285
PMCID: PMC8473977

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