Performance of DNA methylation analysis of ASCL1 , LHX8 , ST6GALNAC5 , GHSR , ZIC1 and SST for the triage of HPV ‐positive women: Results from a Dutch primary HPV ‐based screening cohort

Abstract excerpt

Methylation of host-cell deoxyribonucleic acid (DNA) has been proposed as a promising biomarker for triage of high-risk (hr) human papillomavirus (HPV) positive women at screening. Our study aims to validate recently identified host-cell DNA methylation markers for triage in an hrHPV-positive cohort derived from primary HPV-based cervical screening in The Netherlands. Methylation markers ASCL1, LHX8, ST6GALNAC5,...

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