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Triage of human papillomavirus infected women by methylation analysis in first-void urine

12 Apr 2021

Abstract excerpt

Host cell DNA methylation analysis in urine provides promising triage markers for women diagnosed with a high-risk (HR) human papillomavirus (HPV) infection. In this study, we have investigated a panel of six host cell methylation markers (GHSR, SST, ZIC1, ASCL1, LHX8, ST6GALNAC5) in cervicovaginal secretions collected within the first part of the urine void (FVU) from a referral population. Cytology, histology,...

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PMID: 33846517
DOI: 10.1038/s41598-021-87329-1

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