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Evaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening

26 Apr 2023

Abstract excerpt

BACKGROUND: Host-cell DNA methylation analysis can be used to triage women with high-risk human papillomavirus (HPV)-positive self-collected cervicovaginal samples, but current data are restricted to under-/never-screened women and referral populations. This study evaluated triage performance in women who were offered primary HPV self-sampling for cervical cancer screening. METHODS: Self-collected samples from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37100874
DOI: 10.1038/s41416-023-02277-z

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