Article
Rapid and accurate SNP genotyping of clonal bacterial pathogens with BioHansel.
Microbial genomics - 1 Sept 2021
Labbé Geneviève, Kruczkiewicz Peter, Robertson James, Mabon Philip, Schonfeld Justin, Kein Daniel, Rankin Marisa A, Gopez Matthew, Hole Darian, Son David, Knox Natalie, Laing Chad R, Bessonov Kyrylo, Taboada Eduardo N, Yoshida Catherine, Ziebell Kim, Nichani Anil, Johnson Roger P, Van Domselaar Gary, Nash John H E
Abstract excerpt
Hierarchical genotyping approaches can provide insights into the source, geography and temporal distribution of bacterial pathogens. Multiple hierarchical SNP genotyping schemes have previously been developed so that new isolates can rapidly be placed within pre-computed population structures, without the need to rebuild phylogenetic trees for the entire dataset. This classification approach has, however, seen...
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