SMAD3 rs36221701 T>C polymorphism impacts COPD susceptibility in the Kashi population.

doi:10.1016/j.gene.2021.145970

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Article

SMAD3 rs36221701 T>C polymorphism impacts COPD susceptibility in the Kashi population.

Gene - 15 Jan 2022

Gong Hui, Ren Jie, Xu Jingran, Zhong Xuemei, Abudureheman Zulipikaer, Yilamujiang Subinuer, Xie Chengxin, Ma Tao, Li Feifei, Tang Lifeng, Xu Aimin, Li Li

Abstract excerpt

Small mother against decapentaplegic (SMAD) family member 3 (SMAD3) is well correlated with the inflammatory response of chronic obstructive pulmonary disease (COPD). A previous study indicated that the single nucleotide polymorphism (SNP) rs36221701 of SMAD3 was related to the risk of inflammatory disease. Hence, given the pathogenesis of COPD is intently associated with smoking and gene polymorphism, this study...

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PMID: 34547372
DOI: 10.1016/j.gene.2021.145970

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