Article
Single-nucleotide polymorphisms in SMAD3 are associated with chronic obstructive pulmonary disease.
Experimental biology and medicine (Maywood, N.J.) - 1 May 2010
Yang Ting, Ying Binwu, Song Xingbo, Zhang Sizhong, Fan Hong, Xu Dan, Wang Tao, Liu Daishun, Wen Fuqiang
Abstract excerpt
The aim of this study was to determine the frequencies of single-nucleotide polymorphisms (SNPs) in the Smad3 gene in the Chinese population and their possible association with chronic obstructive pulmonary disease (COPD). The frequency distribution of nine SNPs in the introns of the Smad3 gene was determined in both the COPD patients and control groups by the TaqMan polymerase chain reaction method using a minor...
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