Article
Brg1 mutation alters oxidative stress responses in glioblastoma.
Neurochemistry international - 1 Nov 2021
Gowda Pruthvi, Lathoria Kirti, Umdor Sonia B, Sen Ellora
Abstract excerpt
Increasing evidences suggest that the SWI/SNF chromatin remodeling complex involved in the organization of chromatin architecture via ATP hydrolysis, plays an important role in human cancer. As TCGA gene expression analyses revealed signature of enhanced oxidative stress in GBMs harbouring Brg1mutations, we examined the involvement of ATPase subunit of BRG1 in regulating oxidative stress responses in glioma....
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