Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biomedical Data Commons (BMDC) prioritizes B-lymphocyte non-coding genetic variants in Type 1 Diabetes.

PLoS computational biology - 1 Sept 2021

Piekos Samantha N, Gaddam Sadhana, Bhardwaj Pranav, Radhakrishnan Prashanth, Guha Ramanathan V, Oro Anthony E

Abstract excerpt

The repurposing of biomedical data is inhibited by its fragmented and multi-formatted nature that requires redundant investment of time and resources by data scientists. This is particularly true for Type 1 Diabetes (T1D), one of the most intensely studied common childhood diseases. Intense investigation of the contribution of pancreatic β-islet and T-lymphocytes in T1D has been made. However, genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Diabetes Mellitus, Type 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Regulatory Networks

Share to HLA-DQ beta-Chains

Share to HLA-DRB1 Chains

Share to Ikaros Transcription Factor

Share to Interleukin-2 Receptor alpha Subunit

Share to RNA, Untranslated

Source

Open in PubMed Open full text

Identifiers

PMID: 34543288
DOI: 10.1371/journal.pcbi.1009382
PMCID: PMC8483327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biomedical Data Commons (BMDC) prioritizes B-lymphocyte non-coding genetic variants in Type 1 Diabetes.PMID 34543288Read ↗

Leveraging type 1 diabetes human genetic and genomic data in the T1D Knowledge PortalSemantic proximity Read ↗

T1DBase: update 2011, organization and presentation of large-scale data sets for type 1 diabetes research.Semantic proximity Read ↗

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetesSemantic proximity Read ↗

The Type 1 Diabetes T Cell Receptor and B Cell Receptor Repository in the AIRR Data Commons: a practical guide for access, use and contributions through the Type 1 Diabetes AIRR ConsortiumSemantic proximity Read ↗

Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes.Semantic proximity Read ↗

Meta-evolutionary exome analysis identifies novel type 2 diabetes mellitus genes in the UK Biobank and all of us.Semantic proximity Read ↗

T1DBase, a community web-based resource for type 1 diabetes research.Semantic proximity Read ↗

A rare likely pathogenic HLA-DRB1 variant with compromised immunity in severe COVID-19 patient and in-hospital mortality.Semantic proximity Read ↗

Identification of type 2 diabetes subgroups through topological analysis of patient similarity.Semantic proximity Read ↗

The Type 2 Diabetes Knowledge Portal: An open access genetic resource dedicated to type 2 diabetes and related traits.Semantic proximity Read ↗

Type 2 diabetes: genetic data sharing to advance complex disease research.Semantic proximity Read ↗

A genome-wide meta-analysis of six type 1 diabetes cohorts identifies multiple associated loci.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.