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Article

HSP70iQ435A to subdue autoimmunity and support anti-tumor responses.

Cell stress & chaperones - 1 Sept 2021

Jaishankar Dinesh, Cosgrove Cormac, Ramesh Prathyaya, Mahon James, Shivde Rohan, Dellacecca Emilia R, Yang Shiayin F, Mosenson Jeffrey, Guevara-Patiño José A, Le Poole I Caroline

Abstract excerpt

Developing immunosuppressive therapies for autoimmune diseases comes with a caveat that immunosuppression may promote the risk of developing other conditions or diseases. We have previously shown that biolistic delivery of an expression construct encoding inducible HSP70 (HSP70i) with one amino acid modification in the dendritic cell (DC) activating moiety 435-445 (HSP70iQ435A) to mouse skin resulted in...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 34542825
DOI: 10.1007/s12192-021-01229-x
PMCID: PMC8492854

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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