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Proteomics of autism and Alzheimer’s mouse models reveal common alterations in mTOR signaling pathway

17 Sept 2021

Abstract excerpt

Autism spectrum disorder (ASD) and Alzheimer's disease (AD) are two different neurological disorders that share common clinical features, such as language impairment, executive functions, and motor problems. A genetic convergence has been proposed as well. However, the molecular mechanisms of these pathologies are still not well understood. Protein S-nitrosylation (SNO), the nitric oxide (NO)-mediated...

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PMID: 34535637
DOI: 10.1038/s41398-021-01578-2

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