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Article

Genetic association of FKBP5 with trait resilience in Korean male patients with alcohol use disorder.

Scientific reports - 16 Sept 2021

Park Chun Il, Kim Hae Won, Hwang Syung Shick, Kang Jee In, Kim Se Joo

Abstract excerpt

The FKBP5 gene is known to have an important role in alcohol use disorder (AUD) in response to stress and has been reported to affect stress responses by interacting with childhood trauma. This study investigated the effects of the FKBP5 polymorphism rs1360780 and childhood trauma on trait resilience in male patients with AUD. In addition, allele-specific associations between FKBP5 DNA methylation and resilience...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34531492
DOI: 10.1038/s41598-021-98032-6
PMCID: PMC8445975

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