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Article

Apoptotic functions of PDCD10/CCM3, the gene mutated in cerebral cavernous malformation 3.

Stroke - 1 Apr 2009

Chen Leiling, Tanriover Gamze, Yano Hiroko, Friedlander Robert, Louvi Angeliki, Gunel Murat

Abstract excerpt

BACKGROUND AND PURPOSE: Mutations in the Programmed Cell Death 10 (PDCD10) gene cause autosomal dominant familial cerebral cavernous malformations (CCM3). To date, little is known about the function of this gene and its role in disease pathogenesis. METHODS: We examined the effects of overexpress...

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Source

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Identifiers

PMID: 19246713
DOI: 10.1161/STROKEAHA.108.527135
PMCID: PMC2709460

Genes

PDCD10

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19246713-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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