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Article

TGFB1 (rs1800470 and rs1800469) variants are independently associated with disease activity and autoantibodies in rheumatoid arthritis patients.

Clinical and experimental medicine - 1 Feb 2022

Iriyoda Tatiana Mayumi Veiga, Flauzino Tamires, Costa Neide Tomimura, Lozovoy Marcell Alysson Batisti, Reiche Edna Maria Vissoci, Simão Andréa Name Colado

Abstract excerpt

To evaluate the association between TGFB1 + 869 T > C (rs1800470) and TGFB1-509 C > T (rs1800469) variants with susceptibility for rheumatoid arthritis (RA), disease activity, presence of rheumatoid factor (RF), anti-cyclic citrullinated peptide (anti-CCP) and TGF-β1 plasma levels. A total of 262 patients with RA and 168 control individuals were tested for the TGFB1 variants using a TaqMan genotyping assay....

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PMID: 34046752
DOI: 10.1007/s10238-021-00725-9

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