Article
Preclinical short QT syndrome models: studying the phenotype and drug-screening.
Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology - 2 Mar 2022
Fan Xuehui, Yang Guoqiang, Kowitz Jacqueline, Duru Firat, Saguner Ardan M, Akin Ibrahim, Zhou Xiaobo, El-Battrawy Ibrahim
Abstract excerpt
Cardiovascular diseases are the main cause of sudden cardiac death (SCD) in developed and developing countries. Inherited cardiac channelopathies are linked to 5-10% of SCDs, mainly in the young. Short QT syndrome (SQTS) is a rare inherited channelopathy, which leads to both atrial and ventricular tachyarrhythmias, syncope, and even SCD. International European Society of Cardiology guidelines include as...
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