Article
DNA repair system and prostate cancer progression: the role of NBS1 polymorphism (rs1805794).
DNA and cell biology - 1 Jul 2012
Silva Joana, Teixeira Ana L, Lobo Francisco, Maurício Joaquina, Medeiros Rui
Abstract excerpt
NBS1 plays an important role in the maintenance of genomic integrity, by being involved in cellular response to DNA damage. The NBS1 rs1805794 G>C polymorphism has been investigated in several studies, but its function still remains unclear due to some controversial results. The present work aimed to evaluate the role of this polymorphism in prostate cancer progression, by performing a case-control study...
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