Article
CD24 is a genetic modifier for risk and progression of prostate cancer.
Molecular carcinogenesis - 1 Feb 2017
Zhang Yifan, Li Bingjin, Zhang Xingyi, Sonpavde Guru P, Jiao Kenneth, Zhang Andrea, Zhang Guangxin, Sun Mei, Chu Chengjing, Li Feng, Wang Lizhong, Cui Ranji, Liu Runhua
Abstract excerpt
CD24 plays an oncogenic role in the onset and progression of various human cancers, including prostate cancer. In the present study, we identified two linkage disequilibrium blocks with four recombination hotspot motifs in human CD24 locus. To elucidate whether genetic variants of CD24 are associated with susceptibility to prostate cancer and its disease status, we conducted a case-control association study with...
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