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Article

Molecular origin of the effects of mutation on the structure and mechanical properties of human epithelial keratin K5/K14.

Journal of the mechanical behavior of biomedical materials - 1 Dec 2021

Pan Chien-Yu, Chou Chia-Ching

Abstract excerpt

Epithelial keratin, a type of intermediate filament (IF) protein, is one of the key components in maintaining the stability of the cell nucleus in the epidermis of the skin, the largest organ in the human body. It absorbs water and withstands external pressure, affecting the structural stability and mechanical properties of the skin. Epidermolysis bullosa simplex (EBS) is a rare genetic skin disease related to...

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Identifiers

PMID: 34509171
DOI: 10.1016/j.jmbbm.2021.104798

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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