Article
Management and Outcomes of Blast Transformed Chronic Myelomonocytic Leukemia.
Current hematologic malignancy reports - 1 Oct 2021
Hammond Danielle, Montalban-Bravo Guillermo
Abstract excerpt
PURPOSE OF REVIEW: Despite recent advances in the treatment of de novo acute myeloid leukemia (AML), AML arising from antecedent chronic myelomonocytic leukemia (CMML) continues to have dismal outcomes. While the unique biological drivers of CMML and subsequent leukemic transformation (LT) have been revealed with advances in molecular characterization, this has not yet translated to the bedside. Here, we review...
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