Article
Genetically Encoded Protein Thermometer Enables Precise Electrothermal Control of Transgene Expression
8 Sept 2021
Abstract excerpt
Body temperature is maintained at around 37 °C in humans, but may rise to 40 °C or more during high-grade fever, which occurs in most adults who are seriously ill. However, endogenous temperature sensors, such as ion channels and heat-shock promoters, are fully activated only at noxious temperatures above this range, making them unsuitable for medical applications. Here, a genetically encoded protein thermometer...
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