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Two distinct Sertoli cell states are regulated via germ cell crosstalk†

7 Sept 2021

Abstract excerpt

Sertoli cells are a critical component of the testis environment for their role in maintaining seminiferous tubule structure, establishing the blood-testis barrier, and nourishing maturing germ cells in a specialized niche. This study sought to uncover how Sertoli cells are regulated in the testis environment via germ cell crosstalk in the mouse. We found two major clusters of Sertoli cells as defined by their...

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PMID: 34494084
DOI: 10.1093/biolre/ioab160

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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