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Article

A missense variant rs2585405 in clock gene PER1 is associated with the increased risk of noise-induced hearing loss in a Chinese occupational population.

BMC medical genomics - 8 Sept 2021

Chen Hao, Ding Xuexue, Ding Enmin, Chen Mengyao, Wang Huimin, Yang Guangzhi, Zhu Baoli

Abstract excerpt

OBJECTIVE: To investigate the potential association of cochlear clock genes (CRY1, CRY2, PER1, and PER2), the DNF gene (brain-derived neurotrophic factor), and the NTF3 gene (neurotrophin3) with susceptivity to noise-induced hearing loss (NIHL) among Chinese noise-exposed workers. METHODS: A nested case-control study was performed with 2056 noise-exposed workers from a chemical fiber factory and an energy company...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34493277
DOI: 10.1186/s12920-021-01075-x
PMCID: PMC8425122

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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