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Article

Single nucleotide polymorphisms in JNK1 are associated with susceptibility to noise-induced hearing loss in a Chinese population.

International archives of occupational and environmental health - 1 Jul 2021

Sun Dawei, Wang Boshen, Guo Haoran, Wang Ning, Gao Dengfeng, Zhu Baoli

Abstract excerpt

PURPOSE: This study intended to explore the effect of C-Jun N-terminal kinases 1 (JNK1) polymorphisms on the sensitivity of individual hearing loss. METHODS: A total of 1333 subjects, including 683 NIHL workers and 650 normal-hearing workers from east China, were included in this cross-sectional study. Genotyping of three JNK1 single nucleotide polymorphisms (rs9284, rs8428, and rs11598320) was performed. The...

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Share to Asian People
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Share to Genetic Predisposition to Disease
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Share to Mitogen-Activated Protein Kinase 8
Share to Polymorphism, Single Nucleotide

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PMID: 33433696
DOI: 10.1007/s00420-020-01644-0

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