Article
Genetic variation in KCNQ4 gene is associated with susceptibility to noise-induced hearing loss in a Chinese population.
Environmental toxicology and pharmacology - 1 Oct 2018
Guo Haoran, Ding Enmin, Sheng Rongjian, Cheng Jian, Cai Wenyan, Guo Jiadi, Wang Ning, Zhang Hengdong, Zhu Baoli
Abstract excerpt
Noise-induced hearing loss (NIHL), one of the most widespread occupational health risks worldwide, is a kind of complex disorder resulting from both genetic and environmental factors. KCNQ4 channels are crucial to the internal ear potassium recycling. To explore whether KCNQ4 polymorphism is associated with individual susceptibility to NIHL, we performed this genetic association study on 571 NIHL cases and 639...
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