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Article

Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China.

BMC medical genomics - 11 Jan 2024

Wu Shan, Wu Zhidan, Chen Manlian, Zhong Xiangbin, Gu Haoyan, Du Wenjing, Liu Weidong, Lang Li, Wang Junyi

Abstract excerpt

BACKGROUND: This study aimed to screen and validate noise-induced hearing loss (NIHL) associated single nucleotide polymorphisms (SNPs), construct genetic risk prediction models, and evaluate higher-order gene-gene, gene-environment interactions for NIHL in Chinese population. METHODS: First, 83 cases and 83 controls were recruited and 60 candidate SNPs were genotyped. Then SNPs with promising results were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38212800
DOI: 10.1186/s12920-023-01790-7
PMCID: PMC10785407

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