Article
Identification of a Region in Shigella flexneri WzyB Disrupting the Interaction with WzzpHS2.
Journal of bacteriology - 25 Oct 2021
Leo Vincenzo, Teh Min Yan, Tran Elizabeth N H, Morona Renato
Abstract excerpt
Shigella flexneri can synthesize polysaccharide chains having complex sugars and a regulated number of repeating units. S. flexneri lipopolysaccharide O antigen (Oag) is synthesized by the Wzy-dependent pathway, which is the most common pathway used in bacteria for polysaccharide synthesis. The inner membrane protein WzyB polymerizes the Oag repeat units into chains, while the polysaccharide copolymerases WzzB...
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