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Article

The Wzi outer membrane protein mediates assembly of a tight capsular polysaccharide layer on the Acinetobacter baumannii cell surface.

Scientific reports - 5 Nov 2021

Tickner Jacob, Hawas Sophia, Totsika Makrina, Kenyon Johanna J

Abstract excerpt

Identification of novel therapeutic targets is required for developing alternate strategies to treat infections caused by the extensively drug-resistant bacterial pathogen, Acinetobacter baumannii. As capsular polysaccharide (CPS) is a prime virulence determinant required for evasion of host immune defenses, understanding the pathways for synthesis and assembly of this discrete cell-surface barrier is important....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34741090
DOI: 10.1038/s41598-021-01206-5
PMCID: PMC8571296

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