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Article

Detection of Wzy/Wzz interaction in Shigella flexneri.

Microbiology (Reading, England) - 1 Sept 2015

Nath Pratiti, Morona Renato

Abstract excerpt

The O antigen (Oag) component of Shigella flexneri lipopolysaccharide (LPS) is important for virulence and a protective antigen. It is synthesized by the Wzy-dependent mechanism. S. flexneri Wzy has 12 transmembrane segments and two large periplasmic loops. The modal chain length of the Oag is determined by Wzz. Experimental evidence supports multi-protein interactions in the Wzy-dependent pathway. However,...

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Identifiers

PMID: 26296569
DOI: 10.1099/mic.0.000132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Detection of Wzy/Wzz interaction in Shigella flexneri.PMID 26296569Read ↗

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Structural and Biochemical Analysis of a Single Amino-Acid Mutant of WzzBSF That Alters Lipopolysaccharide O-Antigen Chain Length in Shigella flexneri.Semantic proximity Read ↗

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