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SARS-CoV-2 B.1.617.2 Delta variant replication and immune evasion

6 Sept 2021

Abstract excerpt

. In vitro, B.1.617.2 is sixfold less sensitive to serum neutralizing antibodies from recovered individuals, and eightfold less sensitive to vaccine-elicited antibodies, compared with wild-type Wuhan-1 bearing D614G. Serum neutralizing titres against B.1.617.2 were lower in ChAdOx1 vaccinees than in BNT162b2 vaccinees. B.1.617.2 spike pseudotyped viruses exhibited compromised sensitivity to monoclonal antibodies...

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PMID: 34488225
DOI: 10.1038/s41586-021-03944-y

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