Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comprehensive Analysis of RUNX and TGF-β Mediated Regulation of Immune Cell Infiltration in Breast Cancer

18 Aug 2021

Abstract excerpt

Runt-related transcription factors (RUNXs) can serve as both transcription activators and repressors during biological development, including immune cell maturation. RUNX factors have both tumor-promoting and tumor-suppressive roles in carcinogenesis. Immune cell infiltration and the tumor immune microenvironment have been found to be key regulators in breast cancer progression, treatment response, and patient...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Epigenetics and DNA Methylation
Share to Ferroptosis and cancer prognosis
Share to Immune cells in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34485309
DOI: 10.3389/fcell.2021.730380

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comprehensive Analysis of RUNX and TGF-β Mediated Regulation of Immune Cell Infiltration in Breast CancerPMID 34485309Read ↗

RUNX Family Regulated Immune-related Genes Predict the Prognosis of Breast CancerSemantic proximity Read ↗

Prognostic Value and Immune Characteristics of RUNX Family in Human Cancers: A Pan-cancer AnalysisSemantic proximity Read ↗

Emerging role of RUNX3 in the regulation of tumor microenvironmentSemantic proximity Read ↗

The Roles of RUNX Family Proteins in Development of Immune Cells.Semantic proximity Read ↗

Bone morphogenetic proteins, activins, and growth and differentiation factors in tumor immunology and immunotherapy resistanceSemantic proximity Read ↗

RUNX family: Oncogenes or tumor suppressors (Review)Semantic proximity Read ↗

RUNX family: Regulation and diversification of roles through interacting proteins.Semantic proximity Read ↗

Expression and Prognosis Analyses of Runt-Related Transcription Factor Family in Human LeukemiaSemantic proximity Read ↗

CTHRC1 is a Potential Prognostic Biomarker and Correlated with Macrophage Infiltration in Breast CancerSemantic proximity Read ↗

A stroma-corrected ZEB1 transcriptional signature is inversely associated with antitumor immune activity in breast cancerSemantic proximity Read ↗

RUNX1 and cancerSemantic proximity Read ↗

RUNX1 as a Novel Molecular Target for Breast Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.