Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A versatile, automated and high-throughput drug screening platform for zebrafish embryos.

Biology open - 15 Sept 2021

Lubin Alexandra, Otterstrom Jason, Hoade Yvette, Bjedov Ivana, Stead Eleanor, Whelan Matthew, Gestri Gaia, Paran Yael, Payne Elspeth

Abstract excerpt

Zebrafish provide a unique opportunity for drug screening in living animals, with the fast-developing, transparent embryos allowing for relatively high-throughput, microscopy-based screens. However, the limited availability of rapid, flexible imaging and analysis platforms has limited the use of zebrafish in drug screens. We have developed an easy-to-use, customisable automated screening procedure suitable for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Models, Animal
Share to Algorithms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug Evaluation, Preclinical

Share to Embryo, Nonmammalian

Share to High-Throughput Screening Assays

Share to Phenotype

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 34472582
DOI: 10.1242/bio.058513
PMCID: PMC8430230

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A versatile, automated and high-throughput drug screening platform for zebrafish embryos.PMID 34472582Read ↗

Automated image-based phenotypic analysis in zebrafish embryos.Semantic proximity Read ↗

Automated, high-throughput quantification of EGFP-expressing neutrophils in zebrafish by machine learning and a highly-parallelized microscopeSemantic proximity Read ↗

Technology for high-throughput screens: the present and future using zebrafish.Semantic proximity Read ↗

Automated feature detection and imaging for high-resolution screening of zebrafish embryos.Semantic proximity Read ↗

Zebrafish as a model for normal and malignant hematopoiesisSemantic proximity Read ↗

Flight for fish in drug discovery: a review of zebrafish-based screening of molecules.Semantic proximity Read ↗

Quantitative Geometric Modeling of Blood Cells from X-ray Histotomograms of Whole Zebrafish LarvaeSemantic proximity Read ↗

The Importance of Zebrafish in Biomedical ResearchSemantic proximity Read ↗

AZBA: A 3D Adult Zebrafish Brain Atlas for the Digital AgeSemantic proximity Read ↗

Development of an automated imaging pipeline for the analysis of the zebrafish larval kidney.Semantic proximity Read ↗

Automated analysis of zebrafish images for phenotypic changes in drug discovery.Semantic proximity Read ↗

Assaying hematopoiesis using zebrafish.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.