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Article

Development of an automated imaging pipeline for the analysis of the zebrafish larval kidney.

PloS one - 1 Jan 2013

Westhoff Jens H, Giselbrecht Stefan, Schmidts Miriam, Schindler Sebastian, Beales Philip L, Tönshoff Burkhard, Liebel Urban, Gehrig Jochen

Abstract excerpt

The analysis of kidney malformation caused by environmental influences during nephrogenesis or by hereditary nephropathies requires animal models allowing the in vivo observation of developmental processes. The zebrafish has emerged as a useful model system for the analysis of vertebrate organ development and function, and it is suitable for the identification of organotoxic or disease-modulating compounds on a...

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PMID: 24324758
DOI: 10.1371/journal.pone.0082137
PMCID: PMC3852951

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