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Adropin correlates with aging-related neuropathology in humans and improves cognitive function in aging mice

30 Aug 2021

Abstract excerpt

The neural functions of adropin, a secreted peptide highly expressed in the brain, have not been investigated. In humans, adropin is highly expressed in astrocytes and peaks during critical postnatal periods of brain development. Gene enrichment analysis of transcripts correlating with adropin expression suggests processes relevant to aging-related neurodegenerative diseases that vary with age and dementia state,...

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PMID: 34462439
DOI: 10.1038/s41514-021-00076-5

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