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Frontiers of Model Animals for Neuroscience: Two Prosperous Aging Model Animals for Promoting Neuroscience Research

1 Jan 2013

Abstract excerpt

A model animal showing spontaneous onset is a useful tool for investigating the mechanism of disease. Here, I would like to introduce two aging model animals expected to be useful for neuroscience research: the senescence-accelerated mouse (SAM) and the klotho mouse. The SAM was developed as a mouse showing a senescence-related phenotype such as a short lifespan or rapid advancement of senescence. In particular,...

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PMID: 24172191
DOI: 10.1538/expanim.62.275

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