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Article

Identification of prognostic values defined by copy number variation, mRNA and protein expression of LANCL2 and EGFR in glioblastoma patients.

Journal of translational medicine - 30 Aug 2021

Zhao Hua-Fu, Zhou Xiu-Ming, Wang Jing, Chen Fan-Fan, Wu Chang-Peng, Diao Peng-Yu, Cai Lin-Rong, Chen Lei, Xu Yan-Wen, Liu Jing, Li Zong-Yang, Liu Wen-Lan, Chen Zhong-Ping, Huang Guo-Dong, Li Wei-Ping

Abstract excerpt

BACKGROUND: Epidermal growth factor receptor (EGFR) and lanthionine synthetase C-like 2 (LanCL2) genes locate in the same amplicon, and co-amplification of EGFR and LANCL2 is frequent in glioblastoma. However, the prognostic value of LANCL2 and EGFR co-amplification, and their mRNA and protein expression in glioblastoma remain unclear yet. METHODS: This study analyzed the prognostic values of the copy number...

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Identifiers

PMID: 34461927
DOI: 10.1186/s12967-021-02979-z
PMCID: PMC8404333

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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