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Article

Longitudinal analysis of individual cfDNA methylome patterns in metastatic prostate cancer

28 Aug 2021

Abstract excerpt

BACKGROUND: Disease progression and therapeutic resistance are hallmarks of advanced stage prostate cancer (PCa), which remains a major cause of cancer-related mortality around the world. Longitudinal studies, coupled with the use of liquid biopsies, offer a potentially new and minimally invasive platform to study the dynamics of tumour progression. Our aim was to investigate the dynamics of personal DNA...

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PMID: 34454584
DOI: 10.1186/s13148-021-01155-w

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