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Article

Distinct patterns of within-host virus populations between two subgroups of human respiratory syncytial virus.

Nature communications - 26 Aug 2021

Lin Gu-Lung, Drysdale Simon B, Snape Matthew D, O'Connor Daniel, Brown Anthony, MacIntyre-Cockett George, Mellado-Gomez Esther, de Cesare Mariateresa, Bonsall David, Ansari M Azim, Öner Deniz, Aerssens Jeroen, Butler Christopher, Bont Louis, Openshaw Peter, Martinón-Torres Federico, Nair Harish, Bowden Rory, Golubchik Tanya, Pollard Andrew J

Abstract excerpt

Human respiratory syncytial virus (RSV) is a major cause of lower respiratory tract infection in young children globally, but little is known about within-host RSV diversity. Here, we characterised within-host RSV populations using deep-sequencing data from 319 nasopharyngeal swabs collected during 2017-2020. RSV-B had lower consensus diversity than RSV-A at the population level, while exhibiting greater...

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Identifiers

PMID: 34446722
DOI: 10.1038/s41467-021-25265-4
PMCID: PMC8390747

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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