Article
Within-host whole-genome deep sequencing and diversity analysis of human respiratory syncytial virus infection reveals dynamics of genomic diversity in the absence and presence of immune pressure.
Journal of virology - 1 Jul 2014
Grad Yonatan H, Newman Ruchi, Zody Michael, Yang Xiao, Murphy Ryan, Qu James, Malboeuf Christine M, Levin Joshua Z, Lipsitch Marc, DeVincenzo John
Abstract excerpt
UNLABELLED: Human respiratory syncytial virus (RSV) is the leading cause of lower respiratory tract disease in infants and young children and an important respiratory pathogen in the elderly and immunocompromised. While population-wide molecular epidemiology studies have shown multiple cocirculating RSV genotypes and revealed antigenic and genetic change over successive seasons, little is known about the extent...
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