Article
Direct whole-genome deep-sequencing of human respiratory syncytial virus A and B from Vietnamese children identifies distinct patterns of inter- and intra-host evolution.
The Journal of general virology - 1 Dec 2015
Do Lien Anh Ha, Wilm Andreas, van Doorn H Rogier, Lam Ha Minh, Sim Shuzhen, Sukumaran Rashmi, Tran Anh Tuan, Nguyen Bach Hue, Tran Thi Thu Loan, Tran Quynh Huong, Vo Quoc Bao, Dac Nguyen Anh Tran, Trinh Hong Nhien, Nguyen Thi Thanh Hai, Binh Bao Tinh Le, Le Khanh, Nguyen Minh Tien, Thai Quang Tung, Vo Thanh Vu, Ngo Ngoc Quang Minh, Dang Thi Kim Huyen, Cao Ngoc Huong, Tran Thu Van, Ho Lu Viet, Farrar Jeremy, de Jong Menno, Chen Swaine, Nagarajan Niranjan, Bryant Juliet E, Hibberd Martin L
Abstract excerpt
Human respiratory syncytial virus (RSV) is the major cause of lower respiratory tract infections in children ,2 years of age. Little is known about RSV intra-host genetic diversity over the course of infection or about the immune pressures that drive RSV molecular evolution. We performed whole-genome deep-sequencing on 53 RSV-positive samples (37 RSV subgroup A and 16 RSV subgroup B) collected from the upper...
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