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Article

Whole-genome sequence characterization of respiratory syncytial virus in the Johns Hopkins Health System during the 2024-2025 respiratory season.

Microbiology spectrum - 4 Nov 2025

Zhuang Ting Xuan, Fall Amary, Norton Julie M, Abdullah Omar, Villafuerte David A, Pekosz Andrew, Klein Eili, Mostafa Heba H

Abstract excerpt

Respiratory syncytial virus (RSV) remains a leading cause of lower respiratory tract infections in young children, older adults, and immunocompromised individuals worldwide. In 2023, the first RSV vaccines and the widespread use of monoclonal antibodies were approved, underscoring the need for genomic surveillance to monitor their effectiveness and the emergence of antibody-resistant genotypes. This study details...

Read the complete abstract on PubMed

Topics

Humans
Respiratory Syncytial Virus Infections
Respiratory Syncytial Virus, Human
Whole Genome Sequencing
Genome, Viral

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Infant

Child, Preschool

Phylogeny

Child

Female

Male

Seasons

Adult

Middle Aged

Adolescent

Young Adult

Respiratory Tract Infections

Aged

Source

Open in PubMed Open full text

Identifiers

PMID: 41055398
DOI: 10.1128/spectrum.02065-25
PMCID: PMC12584621

Provenance

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