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A new perspective on protecting the blood-retinal barrier against injury in diabetic retinopathy: mitophagy

3 Sept 2025

Abstract excerpt

The blood-retinal barrier (BRB) comprises the inner blood-retinal barrier (iBRB) and the outer blood-retinal barrier (oBRB). The integrity of the BRB is essential to maintaining stability of the retinal microenvironment. Mitophagy plays a crucial role in maintaining organellar integrity by regulating mitochondrial quality and quantity. High glucose-induced mitophagy dysfunction contributes to diabetic retinopathy...

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Autophagy in Disease and Therapy
Retinal Diseases and Treatments
Retinal Imaging and Analysis

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40969374
DOI: 10.3389/fendo.2025.1617797

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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