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Article

Rosetta:MSF:NN: Boosting performance of multi-state computational protein design with a neural network.

PloS one - 1 Jan 2021

Nazet Julian, Lang Elmar, Merkl Rainer

Abstract excerpt

Rational protein design aims at the targeted modification of existing proteins. To reach this goal, software suites like Rosetta propose sequences to introduce the desired properties. Challenging design problems necessitate the representation of a protein by means of a structural ensemble. Thus, Rosetta multi-state design (MSD) protocols have been developed wherein each state represents one protein conformation....

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PMID: 34437621
DOI: 10.1371/journal.pone.0256691
PMCID: PMC8389498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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