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Article

Structural basis of malarial parasite RIFIN-mediated immune escape against LAIR1.

Cell reports - 24 Aug 2021

Xie Yijia, Li Xin, Chai Yan, Song Hao, Qi Jianxun, Gao George F

Abstract excerpt

Malaria infection by Plasmodium falciparum continues to pose a global threat to the human population. P. falciparum expresses variable erythrocyte surface antigens such as RIFINs. Public antibodies with LAIR1 insertion have been identified from malarial patients against a subset of RIFINs. In this study, we solve a LAIR1-binding RIFIN structure: the complex structures of two RIFINs bound to mutated or wild-type...

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Share to Antibodies, Protozoan
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Share to Erythrocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34433057
DOI: 10.1016/j.celrep.2021.109600

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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