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Article

Structural basis for RIFIN-mediated activation of LILRB1 in malaria.

Nature - 1 Nov 2020

Harrison Thomas E, Mørch Alexander M, Felce James H, Sakoguchi Akihito, Reid Adam J, Arase Hisashi, Dustin Michael L, Higgins Matthew K

Abstract excerpt

The Plasmodium species that cause malaria are obligate intracellular parasites, and disease symptoms occur when these parasites replicate in human blood. Despite the risk of immune detection, the parasite delivers proteins that bind to host receptors on the cell surfaces of infected erythrocytes. In the causative parasite of the most deadly form of malaria in humans, Plasmodium falciparum, RIFINs form the largest...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32650338
DOI: 10.1038/s41586-020-2530-3
PMCID: PMC7116854

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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