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Article

Emergence and expansion of SARS-CoV-2 B.1.526 after identification in New York.

Nature - 1 Sept 2021

Annavajhala Medini K, Mohri Hiroshi, Wang Pengfei, Nair Manoj, Zucker Jason E, Sheng Zizhang, Gomez-Simmonds Angela, Kelley Anne L, Tagliavia Maya, Huang Yaoxing, Bedford Trevor, Ho David D, Uhlemann Anne-Catrin

Abstract excerpt

SARS-CoV-2 infections have surged across the globe in recent months, concomitant with considerable viral evolution1-3. Extensive mutations in the spike protein may threaten the efficacy of vaccines and therapeutic monoclonal antibodies4. Two signature spike mutations of concern are E484K, which has a crucial role in the loss of neutralizing activity of antibodies, and N501Y, a driver of rapid worldwide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34428777
DOI: 10.1038/s41586-021-03908-2
PMCID: PMC8481122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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