Article
Increased Menopausal Age Reduces the Risk of Parkinson's Disease: A Mendelian Randomization Approach.
Movement disorders : official journal of the Movement Disorder Society - 1 Oct 2021
Kusters Cynthia D J, Paul Kimberly C, Duarte Folle Aline, Keener Adrienne M, Bronstein Jeff M, Bertram Lars, Hansen Johnni, Horvath Steve, Sinsheimer Janet S, Lill Christina M, Ritz Beate R
Abstract excerpt
BACKGROUND: Studies of Parkinson's disease (PD) and the association with age at menarche or menopause have reported inconsistent findings. Mendelian randomization (MR) may address measurement errors because of difficulties accurately reporting the age these life events occur. OBJECTIVE: We used MR to assess the association between age at menopause and age at menarche with PD risk. METHODS: We performed inverse...
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